mk2866 is all at once first thing in the morning
gw501516 is dosed all at once 30 minutes prior to your workout and on non workout days, all at once in the a.m.
the others really do not matter... i always dose serms and ancillaries before bed just in case of any side effects but generally you dont have to worry about it as long as they are dosed accordingly however i am one that always uses caution with everything