Hi! I got here some anadrol, and was thinking of doing a cycle with 50 milligrams every day for 6 weeks. I think the cycle length and dosage are correct. But I am lost with the anti-estrogens I will need. What should I use - AI or SERM? People keep telling me different things, and can't explain why.
Anadrol cycle: SERM or AI?
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cbbram
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I would run it 50mg ed with Test Cyp 200-250mg... Aromasin 12.5mg eod.
I'm on TRT so I'm not real knowledgeable on PCT.
Also I personally wouldn't run Anadrol longer than 4 weeks... Your liver will thank you... Test Cyp 10-12weeks
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Anadrol is quite a special steroid in that sense, since in spite of being a DHT derivative, which can not aromatise into estrogen, it still causes estrogen related side effects. It is still not 100% clear to the scientific community to as how anadrol is capable of causing estrogen related side effects, but there seems to be a general consensus that it can directly activate the estrogen receptors without going through modifications. Therefore, it is useless to use AI's on anadrol cycles, since the aromatase enzymes are not involved in the estrogen related side effects. Therefore, only one option is left here - to reduce the estrogen receptors that are activated by anadrol, and the best compound for this are the selectice estrogen receptor modulators (SERM), such as nolvadex, which should be taken at a dosage of 50 mgs per day.
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cbbram
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Very true and very good info!
The Oxymetholone hormone does not aromatize. The aromatase enzyme does not affect it, which is responsible for the conversion of testosterone to estrogen. Further, it is not a progestin and carries no progesterone nature, however, it remains highly estrogenic. How or why it is so estrogenic is a bit of a mystery. There are some theories and the most solid is that Oxymetholone can activate the estrogen receptors to a stronger degree than many other steroids.
Due to the estrogenic nature of Anadrol, gynecomastia can be a real concern, as can excess water retention. In order to protect from gynecomastia you will need an anti-estrogen medication. Anti-estrogens will also have a positive effect on water retention, but when it comes to their use with Anadrol there is an interesting note. The common anti-estrogens used by performance athletes include serms like nolvadex and Aromatase Inhibitors like aromasin. AI’s are by far the most effective at controlling estrogen as they inhibit aromatization and lower the body’s estrogen levels. SERM’s do not inhibit or lower estrogen but attach to the receptors in the place of estrogen. However, in this case it’s important to remember there is no aromatization going on, there is nothing for an AI to inhibit. They will still be the most effective means of protection due to their reducing properties, but some will find SERM’s to be enough. As an added bonus, SERM’s will not negatively affect cholesterol, while some AI’s like arimidex will.
A final note, controlling excess water retention is very important. If excess water retention gets out of hand it can have a negative impact on blood pressure.
[2] Androgenic
Anadrol carries with it some strong androgenic related side effects despite its rather low androgenicity. The androgenic side effects of Anadrol can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. These are genetically based side effects. For example, many who supplement will not have a problem with acne, but those who are genetically sensitive may find they have a problem. It should also be noted; 5-alpha reductase inhibitors will not affect this steroids androgenicity. It is the 5-alpha reductase enzyme that causes testosterone to reduce to DHT, but in this case there is nothing to inhibit as Oxymetholone is already a DHT compound.
Due to the estrogenic nature of Anadrol, gynecomastia can be a real concern, as can excess water retention. In order to protect from gynecomastia you will need an anti-estrogen medication. Anti-estrogens will also have a positive effect on water retention, but when it comes to their use with Anadrol there is an interesting note. The common anti-estrogens used by performance athletes include serms like nolvadex and Aromatase Inhibitors like aromasin. AI’s are by far the most effective at controlling estrogen as they inhibit aromatization and lower the body’s estrogen levels. SERM’s do not inhibit or lower estrogen but attach to the receptors in the place of estrogen. However, in this case it’s important to remember there is no aromatization going on, there is nothing for an AI to inhibit. They will still be the most effective means of protection due to their reducing properties, but some will find SERM’s to be enough. As an added bonus, SERM’s will not negatively affect cholesterol, while some AI’s like arimidex will.
A final note, controlling excess water retention is very important. If excess water retention gets out of hand it can have a negative impact on blood pressure.
[2] Androgenic
Anadrol carries with it some strong androgenic related side effects despite its rather low androgenicity. The androgenic side effects of Anadrol can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. These are genetically based side effects. For example, many who supplement will not have a problem with acne, but those who are genetically sensitive may find they have a problem. It should also be noted; 5-alpha reductase inhibitors will not affect this steroids androgenicity. It is the 5-alpha reductase enzyme that causes testosterone to reduce to DHT, but in this case there is nothing to inhibit as Oxymetholone is already a DHT compound.
This is some great information that I did not see anywhere, and everybody recommended me to use AI's with anadrol. Now I see that those are useless, so I will use tamoxifen - luckily I still got quite a good bunch of it left from before. Thanks everybody for the interesting conversation here!
absolutely brother... that's what we are for... we all learn from one another and grow as one... don't ever hesitate to ask questions bro
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