Question for Buen on trt

[Mb50]

I was wondering if you had any experience with doing low dose ed or eod injections for trt. The reason I'm asking is my shbg is very low 6.6 nmol/l with a range of 16.5-55.9 and total test is 510 ng/dl with a range of 348-1197. I've read that men with low shbg sometimes have better numbers with low dose ed or eod injections. Currently I'm taking t cyp 160mg split 2x a wk. injection was Monday pm and bloods drawn Thursday am. I started on 120mg split 2x a week and it was increased several times to the current 160mg. Obviously increasing the dose isn't working to increase total t numbers. I have an appointment with my doc in two weeks and obviously will discuss this with him I'm just weighing my options so I'm prepared when we talk. Thanks bro

 

[RickRock]

I was wondering if you had any experience with doing low dose ed or eod injections for trt. The reason I'm asking is my shbg is very low 6.6 nmol/l with a range of 16.5-55.9 and total test is 510 ng/dl with a range of 348-1197. I've read that men with low shbg sometimes have better numbers with low dose ed or eod injections. Currently I'm taking t cyp 160mg split 2x a wk. injection was Monday pm and bloods drawn Thursday am. I started on 120mg split 2x a week and it was increased several times to the current 160mg. Obviously increasing the dose isn't working to increase total t numbers. I have an appointment with my doc in two weeks and obviously will discuss this with him I'm just weighing my options so I'm prepared when we talk. Thanks bro

I'm pretty sure Buen does test p EOD if I remember right for TRT.

How long after injections are you getting bloods? What was your test at with other doses? You may need closer to 200mg per week like me. That puts me around 900 and I'm happy there

 

[Mb50]

I do have thyroid issues as well but I'm on levothyroxine and numbers are in range. Injection Monday pm bloods Thursday am. Initially I'd be at 900 to 1000 at trough but numbers have been slowly decreasing.

 

[RickRock]

I do have thyroid issues as well but I'm on levothyroxine and numbers are in range. Injection Monday pm bloods Thursday am. Initially I'd be at 900 to 1000 at trough but numbers have been slowly decreasing.

Number shouldn't be decreasing that quickly if you are using test c. It has an 8 day half life. About 6 days after my pin I'm at 900 and I only pin once per week. That's a bit strange.

 

[Mb50]

I agree I thought maybe the compounding pharmacy I used had a weak batch maybe and my doc got their test number for the lot mine was from 200 mg test c tested at 204.3 mg/ ml. I have read men with low shbg may metabolize test more rapidly thus the more frequent injections.

 

[hman]

Isn't it a good thing to have a lower shbg....and when using cyp I get bloods done 7days after Injection

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[hman]

When u say ed do u mean subq or r u doing IM injections for trt

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[Mb50]

IM. And since injection is 2x a week bloods are always done before next injection

 

[Mb50]

Lower shbg is ok but not so much lower than the normal range like mine

 

[buen]

I pin test prop daily..It just works best for me

Have you checked your Free test range...has it been changing also?

I'm not very versed on low SHBG....but it seems like some guys with low SHBG do seem to metabolize their TRT dose rapidly....so more frequent pinning might make sense
I think there is a lot of good discussion on it at some of the men's health sites dealing with TRT

Low SHBG is associated with obesity
Low SHBG can be a warning of serious disease...
SHBG is often a flag or warning signal of insulin and blood sugar issues.
SHBG does not cause insulin resistance but can indicate it.
SHBG has been linked with elevated CRP (C-Reactive Protein)


The bottom line is..your endo needs to find the cause of your low SHBG...insulin, estradiol. prolactin, thyroid are all tied together..it can be complex