Consuming orals question

[CobraMuscle]

Hey guys just had a quick question on how to take your aas orals. Do you need to take them with food? Also does anyone drink grape juice with it because its supposed to help the oral get better absorbed? How do y'all split your doses?

 

[TheSVPdeal]

I go empty stomach

 

[drb_iac]

Hey guys just had a quick question on how to take your aas orals. Do you need to take them with food? Also does anyone drink grape juice with it because its supposed to help the oral get better absorbed? How do y'all split your doses?

Man I dont think it matters. It used to be, or maybe still is, said that they had to be divided doses, but I didnt find that it made much difference. The grape juice thing came about when creatine hit the market and it was thought that the grape juice would elicit an insulin response which in turn would jam the creatine into your cells better. I never did buy that and thru experimentation and record keeping never found any of that to be the case. Just take your dose and be done with it. Too much ruminating and science sometimes. Take it, workout, eat right, forget about it.

 

[RickRock]

Re: RE: Consuming orals question

Hey guys just had a quick question on how to take your aas orals. Do you need to take them with food? Also does anyone drink grape juice with it because its supposed to help the oral get better absorbed? How do y'all split your doses?

There is some data supporting the fact that your orals should be consumed with meals for best bioavailability and absorption when possible. This helps the compounds from being degraded by stomach acid. Especially meals with a small amount of fat content which seems to coat the molecule for best absorption.

It won't make a big difference either way, but I would take them with food when possible

 

[Saiyan]

William Llewellyn's book "Anabolics 10th edition" states this.
“Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

 

[DylanGemelli]

William Llewellyn's book "Anabolics 10th edition" states this.
“Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

you'll find arguments either way on this subject... regardless, i take mine on an empty stomach but im assuming you mean grapefruit juice not grape...

as far as dosing... take your first serving of orals in the morning, then 4 hours later take your first dose of cycle protection, then 4 hours later take your second oral dose then 4 hours later take your last dose of support...

 

[Saiyan]

Ok cool Dylan. I was just passing on a direct source, I just recently finished reading that book and thought it was an awesome starting point, other than Internet and forums.

And I think he really did mean grape and not grapefruit. Early 2014 I was looking into prohormones. I bought some but never took them thankfully. But while researching, I found that a majority of people said grape and nothing citrus. I guess their reasoning was that the acid was bad for absolution or something. That could be what he is referring to as well.

 

[DylanGemelli]

Ok cool Dylan. I was just passing on a direct source, I just recently finished reading that book and thought it was an awesome starting point, other than Internet and forums.

And I think he really did mean grape and not grapefruit. Early 2014 I was looking into prohormones. I bought some but never took them thankfully. But while researching, I found that a majority of people said grape and nothing citrus. I guess their reasoning was that the acid was bad for absolution or something. That could be what he is referring to as well.

grapefruit juice is what you want with orals... that is what provides the best possible absorption... its all good brother... im happy to help and also always happy to hear other information passed along etc.... its always good to ask questions bro...

 

[Saiyan]

Ok cool Dylan. I was just passing on a direct source, I just recently finished reading that book and thought it was an awesome starting point, other than Internet and forums.

And I think he really did mean grape and not grapefruit. Early 2014 I was looking into prohormones. I bought some but never took them thankfully. But while researching, I found that a majority of people said grape and nothing citrus. I guess their reasoning was that the acid was bad for absolution or something. That could be what he is referring to as well.

grapefruit juice is what you want with orals... that is what provides the best possible absorption... its all good brother... im happy to help and also always happy to hear other information passed along etc.... its always good to ask questions bro...

Thanks for clarifying that for me as well as the OP. I'll keep that in mind when I get to that point. Lol again all the research I did on PH was probably poor and I would have paid for it dearly in my haste.

 

[RickRock]

William Llewellyn's book "Anabolics 10th edition" states this.
“Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

That's quite interesting. I've always heard the opposite. Like I said though, I don't think it makes a discernible difference either way. Just take them in whatever fashion suits your current schedule best is what I would do

 

[Guest]

All drugs are different. As an example, Viagra with food diminishes effects by 50% or more while Cialis does not have the same issue. So yes, it matters.

As for timing, do the math:

If you took 100mg of an oral with a 9 hour half life at 8 am. By 5pm, you would have 50mg of effective drug in your blood. By 2am, 9 hours later, you would have 25mg of effective drug so forth and so on.

If you split that dose and took 50mg at 8am, by 5pm you would be left with 25mg, pop your other 50mg and now your at 75mg of effective drug. By 2am, 32.5mg.

Split your dose

 

[TheSVPdeal]

All drugs are different. As an example, Viagra with food diminishes effects by 50% or more while Cialis does not have the same issue. So yes, it matters.

As for timing, do the math:

If you took 100mg of an oral with a 9 hour half life at 8 am. By 5pm, you would have 50mg of effective drug in your blood. By 2am, 9 hours later, you would have 25mg of effective drug so forth and so on.

If you split that dose and took 50mg at 8am, by 5pm you would be left with 25mg, pop your other 50mg and now your at 75mg of effective drug. By 2am, 32.5mg.

Split your dose

 

[DylanGemelli]

All drugs are different. As an example, Viagra with food diminishes effects by 50% or more while Cialis does not have the same issue. So yes, it matters.

As for timing, do the math:

If you took 100mg of an oral with a 9 hour half life at 8 am. By 5pm, you would have 50mg of effective drug in your blood. By 2am, 9 hours later, you would have 25mg of effective drug so forth and so on.

If you split that dose and took 50mg at 8am, by 5pm you would be left with 25mg, pop your other 50mg and now your at 75mg of effective drug. By 2am, 32.5mg.

Split your dose

nice bro... all very valid points and very precise... i love it... thanks for posting this