Receptor Saturation Questions

[jjfingers]

When taking multiple versions of SARMs while on testosterone therapy, at what point do androgen receptors become saturated? From an anabolic-androgenic point of view wouldn’t we want more receptors available for testosterone as that hormone is more effective than SARMs? Do receptors treat these compounds preferentially, meaning would a receptor be more likely to utilize testosterone over a SARM or is it first come first serve? At what point would the system be overloaded and not able to utilize any of these compounds at the same time thus flushing them from the system? Sorry for the bombardment of questions. Becoming over curious.

 

[RickRock]

When taking multiple versions of SARMs while on testosterone therapy, at what point do androgen receptors become saturated? From an anabolic-androgenic point of view wouldn’t we want more receptors available for testosterone as that hormone is more effective than SARMs? Do receptors treat these compounds preferentially, meaning would a receptor be more likely to utilize testosterone over a SARM or is it first come first serve? At what point would the system be overloaded and not able to utilize any of these compounds at the same time thus flushing them from the system? Sorry for the bombardment of questions. Becoming over curious.

Androgen receptors never get saturated, on sarms or even AAS for that matter. That is something that has become spread around as false bro science as to the reason that your gains stall out....when in fact the real reason is myostatin. Myostatin is what stalls out your gains during a cycle. Your androgen receptors are always readily available to uptake androgens.

Now to get to the point of the question, the effects on myostatin depends on the nature of the compound and how anabolic/androgenic it is. AAS Has a large impact on myostatin, especially compounds like Tren. Due to sarms being more mild in nature in comparison to AAS, it has a very small minimal impact on myostatin. This is why gains with sarms continue on for up to 12 weeks.....and at that point they start to stall out primarily because of your body becoming adapted to the compound. This is why sarms are so perfect to use in between cycles and as part of a bridge. You can run them right up until a cycle starts, then when you start the cycle with AAS the gains kick off again with the higher amounts of androgens.....and then will stall out like normal once myostatin reaches peak.

I hope this helps clear things up for you

 

[9th Wonder]

Androgen receptors never get saturated, on sarms or even AAS for that matter. That is something that has become spread around as false bro science as to the reason that your gains stall out....when in fact the real reason is myostatin. Myostatin is what stalls out your gains during a cycle. Your androgen receptors are always readily available to uptake androgens.

Now to get to the point of the question, the effects on myostatin depends on the nature of the compound and how anabolic/androgenic it is. AAS Has a large impact on myostatin, especially compounds like Tren. Due to sarms being more mild in nature in comparison to AAS, it has a very small minimal impact on myostatin. This is why gains with sarms continue on for up to 12 weeks.....and at that point they start to stall out primarily because of your body becoming adapted to the compound. This is why sarms are so perfect to use in between cycles and as part of a bridge. You can run them right up until a cycle starts, then when you start the cycle with AAS the gains kick off again with the higher amounts of androgens.....and then will stall out like normal once myostatin reaches peak.

I hope this helps clear things up for you

Well put Rick! The SARMS as a bridge is how I've been doing it for some time. And with the addition of all the new SARMS available, they've become even more versatile

 

[DylanGemelli]

Androgen receptors never get saturated, on sarms or even AAS for that matter. That is something that has become spread around as false bro science as to the reason that your gains stall out....when in fact the real reason is myostatin. Myostatin is what stalls out your gains during a cycle. Your androgen receptors are always readily available to uptake androgens.

Now to get to the point of the question, the effects on myostatin depends on the nature of the compound and how anabolic/androgenic it is. AAS Has a large impact on myostatin, especially compounds like Tren. Due to sarms being more mild in nature in comparison to AAS, it has a very small minimal impact on myostatin. This is why gains with sarms continue on for up to 12 weeks.....and at that point they start to stall out primarily because of your body becoming adapted to the compound. This is why sarms are so perfect to use in between cycles and as part of a bridge. You can run them right up until a cycle starts, then when you start the cycle with AAS the gains kick off again with the higher amounts of androgens.....and then will stall out like normal once myostatin reaches peak.

I hope this helps clear things up for you

rick has been studying this concept for a very long time and is my go to guy on any sort of related question... i could not answer this any better...