Heat degradation is a real concern but depends heavily on the compound and form. Some specifics:
Lyophilized (freeze-dried) peptides in powder form — very heat stable. Peptides in this state can tolerate short periods of ambient and even moderately warm temperatures without significant degradation. The bigger concern is moisture exposure, not heat alone. Short transit times in hot weather (1–3 days) are generally not a problem for powder.
Liquid (reconstituted) peptides and SARMs in solution — significantly more vulnerable to heat. Liquid preparations can degrade meaningfully above 30°C especially for extended periods. If sitting in a hot warehouse or on a truck for multiple days in summer, degradation is plausible. Bacteriostatic water preparations are somewhat more stable but still temperature-sensitive once reconstituted.
For liquid SARMs specifically — the carrier suspension matters. PEG or DMSO-based carriers are more heat-resilient than alcohol-based. Still, extended heat exposure shortens shelf life.
What good vendors do: cold pack with gel ice packs or dry ice for liquid compounds and reconstituted peptides during summer months. This matters especially for anything shipping across the country in July/August. If your order arrives and the ice pack is fully melted but product was never in excessive heat for extended time, it's usually fine — the ice is doing its job.
For lyophilized powder: I wouldn't worry much about standard ground shipping even in summer. For reconstituted liquid: more caution warranted for multi-day transit.
