I never recommend running both. It can be difficult for most to control the sides correctly with that much nandrolone unless experienced enough to know what your body needs and how it reacts to each compound individually
Is it good on cycle? No. Is it going to keep you from gaining? Also no. Your best bet is not doing it for optimal results but I also wouldnt let a cycle dictate how I live my life either. Be sensible and moderate in all things. Find your own balance like so many have so you can enjoy your life...
If you are not on an AI that is probabaly a big reason for your bloat and puffiness. Judging by your estradiol numbers it sounds like you are not on an AI and need one
To answer ypur question you need to be on it to see the benefit and it needs dosed daily to maintain the benefit. The benefit it provides will decrease every day you are off of it. The half life is fairly short so even a few days without and you will notice less benefit in terms of endurance.