Tamoxifen Citrate (Nolvadex)


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Originally designed for the treatment of breast cancer over 30 years ago, Nolvadex (Nolva) quickly found its way into the bodybuilding world. Although when it first became popular in the late 70s and early 80s the use of this SERM was quite misunderstood. Given its original use, Nolva can act directly on breast tissue which is why it quickly found its way into bodybuilding, especially with the infamous estrogenic side effect, Gynecomastia aka “bitch tits”.
Due to its estrogen blocking capabilities Nolva was used on cycle as what we call an Aromatize Inhibitor these days. It’s easy to understand why early bodybuilders thought this could be beneficial, but once we understand the mechanisms in which Nolva acts we will get a better understanding of how to use it the most effectively.
How it works
Nolva is an antagonist of the estrogen receptor via the metabolite 4-hydroxytamoxifen. When this occurs it doesn’t allow circulating estrogen to bind to the receptor. Now we can go back to why early users were using Nolva on cycle; because they assumed that blocking estrogen would ultimately keep estrogen levels in check. This is why many confuse Nolvadex as an AI (Aromatize Inhibitor) but since AI’s potentially decrease estrogen levels and Nolva only blocks estrogen, one can see there is quite a difference.
This leads to an extremely popular and serious issue: The Rebound Effect where users experience a rebound(increase) of estrogen levels once Nolva use has discontinued, because Nolva only blocks estrogen when using, therefore if not used properly a user can experience estrogen related sides including Gynecomastia after their anabolic steroid cycle.
Nolva also has some other properties very similar to those of Clomid, another SERM. It has the ability to stimulate the follicle stimulating hormone (FSH) as well as the luteinizing hormone (LH) via gonadotropin release from the pituitary gland, very similar to Clomid. This is why both Nolva and Clomid are generally utilized during a post cycle therapy (PCT). They ultimately lead to an increase in testosterone levels until the body can begin producing on its own. Remember, when running an anabolic steroid cycle, FSH and LH are greatly suppressed, thus natural testosterone productions will be shut down.

Side Effects
-Changes in mood
-Potential libido changes
-Possible IGF-1 level decreases
-Hot flashes
-Estrogen rebound
Since Nolva has estrogen blocking capabilities especially in breast tissue, it can be used for treatment of Gynecomastia. The dosage can vary greatly but general guidelines are between 20-60mg/ED until Gyno sides have subsided.
Nolva is best used as part of a post cycle therapy due to its ability to stimulate testosterone production. A recommended starting dose is between 20-40mg/day in PCT. Again, PCT lengths and dosages will vary from user to user but the more thorough your PCT the better off one will be in many aspects. Nolva generally is used for 4 weeks in PCT and gets the bodies HTPA started, increasing recovery success.

Additional Notes
Nolva is a powerful SERM no question, but there is some evidence it can increase progestin levels in the body. Therefore it’s unwise to run with compounds that do the same which are primarily nadrolones, such as Deca-Durabolin and Trenbolone. Furthermore, when dosed properly Nolva can be a staple of any PCT and even used alongside Clomid for optimal recovery. Studies have shown that Nolva can potentially increase testosterone levels 150% after just 10 days at 20mg/day. Remember, Nolva should primarily be used in PCT and only in Gynecomastia circumstances. When dosed accurately and used precisely, Nolva can be a very effective tool for proper recovery after an anabolic steroid cycle.

By: Dylan Gemelli
for those who dont want to spend the $$ on caber or prami....

200-300mg of B6 will do 50% of what caber does. its not going to be the same, but if you dont wana spend 135 for 8wks worth, B6 is a good option. Also for guys who are trying to rid or reduce gyno....

B6. Caber isnt necessary. Back in the day, B6 & nolva was all they had.
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