Usually the cheaper product has only trace amounts of what is needs always check the doses of the ingredients I will notice the difference. The 5% nutrition is pretty cheap and is decent for an all around support but if your looking to focus more on liver and kidney health and detox there are other brands that offer what u need. I buy my liver and kidney support supplements separately so I can take the max clinical dose of everything. DGA nutrition detox supplement was a good one Iv used that a couple times.