.jpg "Research Chemical Sciences")
11 HAIR REGENERATION TECHNOLOGIES...2017
"...Pagers, horses & buggies, black & white tv's,
are all in the past. So is Minoxidil, Dutasteride,
Finesteride, and hair transplant surgeries..."
(1) Shiseido/Replicel
(2) Histogen
(3) Brotzu Lotion
(4) RiverTown Therapeutics Inc.
(5) Tsuji-Riken/Organ Technologies
(6) Follica
(7) Follicum
(8) Samumed – SM04554
(9) Allergan – Bimatoprost
(10) Allergan (from Kythera)
(11) Dr. Colin Jahoda & Dr. Angela Chrisiano
----------------------------------------------------
11 HAIR REGENERATION TECHNOLOGIES...EXPLAINED
"...Pagers, horses & buggies, black & white tv's,
are all in the past. So is Minoxidil, Dutasteride,
Finesteride, and hair transplant surgeries..."
(1) Shiseido/Replicel/RCH-01
- cellular-based technology
- Replicel has licensed Shiseido the
rights to bring RCH-01 to the world
- future project involves ips cells...
A treatment using iPS cells would be
very advanced and could potentially
produce an unlimited amount of hair
regrowth.
----------------------------------
- Estimated market release by 3rd
quarter 2018 in Japan
----------------------------------
(2) Histogen/Hair Stimulating Complex (HSC)
- an injectable serum
- effective at regrowing hair at
(1) the temples and (2) the scalp.
- The treatment has been trialed on
both men and women
- stimulate the growth of
(1) new hair follicles
(2) existing hair follicles
----------------------------------
- Potentially on the market in
Mexico in late 2017, 2018.
----------------------------------
(3) Brotzu Lotion
- Dr. Giovanni Brotzu, a vascular surgeon
from Italy noticed that a treatment meant
for vascular insufficiency regrew hair on
patient’s legs.
- Brotzu’s team tested the formula on
people’s scalps. Those tests proved
worthwhile.
- Dr. Brotzu also released a compelling photo
in 2016 of a young girl with alopecia areata
who used the lotion and got impressive results.
----------------------------------
- should be available by the end
of 2018
----------------------------------
(4) RiverTown Therapeutics Inc./RT1640
- In a Phase 1 trial, 100% of the people who
used the treatment had satisfactory hair growth
- reportedly, several people had complete hair
regeneration
- RT1640 is said to restore pigment to regenerated
hair as well.
- folliclethought.com, who tested the product, quotes...
"...results for RT1640 are the most significant
hair regeneration results I have ever
witnessed from a TOPICAL treatment..."
"...Not only does RT1640 (1) regrow hair, it also
(2) restores the pigment to the hair it
regenerates..."
----------------------------------
- Currently raising funds for a
Phase 1B/2A study in 2017.
----------------------------------
(5) Tsuji-Riken/Organ Technologies
- stem cells to grow hair
- a joint venture:
(1) Kyocera
- electronics company
(2) Organ Technologies
- regenerative medicine
Kyocera will be developing the cell
processing devices.
RIKEN and Organ Technologies will be
responsible for the stem cell culturing
and manipulation
----------------------------------
- Kyocera has announced that they aim
for this treatment to be on the market
in 2020.
----------------------------------
(6) Follica/RAIN
- creating tiny wounds in the scalp to create
hair follicle generation.
- two part process
(1) micro-wounding therapy (done in clinic)
(2) treatment package (done at home)
The company has also developed a smart phone
app to help users to keep track of their at home
treatment routines.
- 10 years deep in development
----------------------------------
- Aiming at FDA clearance in
2017 for a commercial release
in 2018.
----------------------------------
(7) Follicum/FOL-S-005
- PEPTIDE HAIR-GROWTH
- PEPTIDE HAIR-GROWTH potential was an accident.
The hair growth effect of this peptide was
discovered accidentally in mice in 2004.
- human peptides for the use of
(1) stimulating hair growth
(2) inhibiting hair growth.
"...growth/inhibition effect..."
- human trials began in early 2016
- have secured two major manufacturing partners for
their peptide technology.
----------------------------------
- Phase 2A trial to conclude in
January 2017.
Those results to follow in early
2017.
----------------------------------
(8) Samumed/SM04554
- activates the Wnt pathway to grow hair.
small molecule topical solution that activates
the Wnt pathway to grow hair.
- 10% overall increase in hair density was observed
in the best responding group
NOTE: Phase 2 results got a mixed response from the
online world of hair growth enthusiasts.
----------------------------------
- Have recently completed the biopsy
analysis phase 2 trial.
Next step, is yet to be announced.
----------------------------------
(9) Allergan/Bimatoprost
- accidental hair growth...
Bimatoprost, a liquid topical solution, originally
developed to treat glaucoma, was discovered to grow
eyelashes superfast.
- Bimatoprost has been FDA approved to grow
a type of body hair, eyelashes.
"if it works on eyelashes...what about scalp hair?"
- has recently been further enhanced to reach the
hair follicles more effectively
----------------------------------
- Phase I trial to be completed in
October 2017.
----------------------------------
(10) Allergan/Kythera
- uses Setipiprant, an oral medication or pill,
for hair growth.
- Kythera announced it acquired the rights from
Cotsarelis to use setipiprant for hair growth.
- Setipiprant is now undergoing a phase 2A clinical
trial in which FINASTERIDE is one of the control
vehicles.
----------------------------------
- Undergoing phase 2A clinial trial
with a completion date of September
2017
----------------------------------
(11) Dr. Colin Jahoda & Dr. Angela Chrisiano/"Rapunzel"
- JAK inhibitor
- Christiano has recently stated...
“we can grow rat hair like it’s no tomorrow"
"we think we can do it with human hair, too.”
PROOF:
Dr. Jahoda implanted his own hair cells into his
wife’s arm and found that his cells grew hair on her
arm all the way back in 1999.
"...his cells grew hair on her arm..."
----------------------------------
- Rapunzel could enter headlines
in 2nd Quarter, 2017
----------------------------------
----------------------------------------------------
REFERENCE:
http://www.folliclethought.com/ultimate-guide-to-hair-regeneration/
"...Pagers, horses & buggies, black & white tv's,
are all in the past. So is Minoxidil, Dutasteride,
Finesteride, and hair transplant surgeries..."
(1) Shiseido/Replicel
(2) Histogen
(3) Brotzu Lotion
(4) RiverTown Therapeutics Inc.
(5) Tsuji-Riken/Organ Technologies
(6) Follica
(7) Follicum
(8) Samumed – SM04554
(9) Allergan – Bimatoprost
(10) Allergan (from Kythera)
(11) Dr. Colin Jahoda & Dr. Angela Chrisiano
----------------------------------------------------
11 HAIR REGENERATION TECHNOLOGIES...EXPLAINED
"...Pagers, horses & buggies, black & white tv's,
are all in the past. So is Minoxidil, Dutasteride,
Finesteride, and hair transplant surgeries..."
(1) Shiseido/Replicel/RCH-01
- cellular-based technology
- Replicel has licensed Shiseido the
rights to bring RCH-01 to the world
- future project involves ips cells...
A treatment using iPS cells would be
very advanced and could potentially
produce an unlimited amount of hair
regrowth.
----------------------------------
- Estimated market release by 3rd
quarter 2018 in Japan
----------------------------------
(2) Histogen/Hair Stimulating Complex (HSC)
- an injectable serum
- effective at regrowing hair at
(1) the temples and (2) the scalp.
- The treatment has been trialed on
both men and women
- stimulate the growth of
(1) new hair follicles
(2) existing hair follicles
----------------------------------
- Potentially on the market in
Mexico in late 2017, 2018.
----------------------------------
(3) Brotzu Lotion
- Dr. Giovanni Brotzu, a vascular surgeon
from Italy noticed that a treatment meant
for vascular insufficiency regrew hair on
patient’s legs.
- Brotzu’s team tested the formula on
people’s scalps. Those tests proved
worthwhile.
- Dr. Brotzu also released a compelling photo
in 2016 of a young girl with alopecia areata
who used the lotion and got impressive results.
----------------------------------
- should be available by the end
of 2018
----------------------------------
(4) RiverTown Therapeutics Inc./RT1640
- In a Phase 1 trial, 100% of the people who
used the treatment had satisfactory hair growth
- reportedly, several people had complete hair
regeneration
- RT1640 is said to restore pigment to regenerated
hair as well.
- folliclethought.com, who tested the product, quotes...
"...results for RT1640 are the most significant
hair regeneration results I have ever
witnessed from a TOPICAL treatment..."
"...Not only does RT1640 (1) regrow hair, it also
(2) restores the pigment to the hair it
regenerates..."
----------------------------------
- Currently raising funds for a
Phase 1B/2A study in 2017.
----------------------------------
(5) Tsuji-Riken/Organ Technologies
- stem cells to grow hair
- a joint venture:
(1) Kyocera
- electronics company
(2) Organ Technologies
- regenerative medicine
Kyocera will be developing the cell
processing devices.
RIKEN and Organ Technologies will be
responsible for the stem cell culturing
and manipulation
----------------------------------
- Kyocera has announced that they aim
for this treatment to be on the market
in 2020.
----------------------------------
(6) Follica/RAIN
- creating tiny wounds in the scalp to create
hair follicle generation.
- two part process
(1) micro-wounding therapy (done in clinic)
(2) treatment package (done at home)
The company has also developed a smart phone
app to help users to keep track of their at home
treatment routines.
- 10 years deep in development
----------------------------------
- Aiming at FDA clearance in
2017 for a commercial release
in 2018.
----------------------------------
(7) Follicum/FOL-S-005
- PEPTIDE HAIR-GROWTH
- PEPTIDE HAIR-GROWTH potential was an accident.
The hair growth effect of this peptide was
discovered accidentally in mice in 2004.
- human peptides for the use of
(1) stimulating hair growth
(2) inhibiting hair growth.
"...growth/inhibition effect..."
- human trials began in early 2016
- have secured two major manufacturing partners for
their peptide technology.
----------------------------------
- Phase 2A trial to conclude in
January 2017.
Those results to follow in early
2017.
----------------------------------
(8) Samumed/SM04554
- activates the Wnt pathway to grow hair.
small molecule topical solution that activates
the Wnt pathway to grow hair.
- 10% overall increase in hair density was observed
in the best responding group
NOTE: Phase 2 results got a mixed response from the
online world of hair growth enthusiasts.
----------------------------------
- Have recently completed the biopsy
analysis phase 2 trial.
Next step, is yet to be announced.
----------------------------------
(9) Allergan/Bimatoprost
- accidental hair growth...
Bimatoprost, a liquid topical solution, originally
developed to treat glaucoma, was discovered to grow
eyelashes superfast.
- Bimatoprost has been FDA approved to grow
a type of body hair, eyelashes.
"if it works on eyelashes...what about scalp hair?"
- has recently been further enhanced to reach the
hair follicles more effectively
----------------------------------
- Phase I trial to be completed in
October 2017.
----------------------------------
(10) Allergan/Kythera
- uses Setipiprant, an oral medication or pill,
for hair growth.
- Kythera announced it acquired the rights from
Cotsarelis to use setipiprant for hair growth.
- Setipiprant is now undergoing a phase 2A clinical
trial in which FINASTERIDE is one of the control
vehicles.
----------------------------------
- Undergoing phase 2A clinial trial
with a completion date of September
2017
----------------------------------
(11) Dr. Colin Jahoda & Dr. Angela Chrisiano/"Rapunzel"
- JAK inhibitor
- Christiano has recently stated...
“we can grow rat hair like it’s no tomorrow"
"we think we can do it with human hair, too.”
PROOF:
Dr. Jahoda implanted his own hair cells into his
wife’s arm and found that his cells grew hair on her
arm all the way back in 1999.
"...his cells grew hair on her arm..."
----------------------------------
- Rapunzel could enter headlines
in 2nd Quarter, 2017
----------------------------------
----------------------------------------------------
REFERENCE:
http://www.folliclethought.com/ultimate-guide-to-hair-regeneration/
